all 3 comments

[–]Corsaer 2 points3 points  (1 child)

Wow this is super cool. Too bad they didn't show the ultrasound images of the mouse colon that the article mentioned.

[–]NickStihl 1 point2 points  (0 children)

Here, here! As weird as it might sound, I'd actually want to see that.

[–]bboyjkang[S] 1 point2 points  (0 children)

Bourdeau RW, Lee-Gosselin A, Lakshmanan A, Farhadi A, Kumar SR, Nety SP et al. (2018)

Acoustic reporter genes for noninvasive imaging of microorganisms in mammalian hosts. Nature 553 (7686):86-90. DOI: 10.1038/nature25021 PMID: 29300010.

Currently, the most popular method is to get bacteria to express fluorescent proteins and then track the microbes through their bioluminescence.

But bioluminescence-based techniques work at depths of only a few millimeters below the body’s surface, and their resolution degrades quickly with depth.

Mikhail G. Shapiro of Caltech and coworkers have now developed a new technique based on ultrasound imaging that improves imaging depth to more than 10 cm and substantially enhances spatial resolution (Nature 2018, DOI: 10.1038/nature25021).