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That’s a very old discussion on a benefit of a divided brain structure in early organisms. I think my non-eloquent answer is that our early evolutionary ancestors had a divided brain structure in order to perform simple tasks more efficiently and there was no evolutionary advantage in selecting a different system.

I went at 12:30 ish. It was terrible. Everything had a long line. The drink ticket line was the first thing I noticed. Then the actual drinks line.... Wtf... Why have drink tickets to begin with?

Food truck lines were not as long but by the time I walked half through I wanted out.

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Was there at 1:30-2:00. Walked up and down the place. Couldn’t find a single food vendor line that seemed shorter than 45-60 minutes. With the intermittent rain I didn’t feel like waiting that long, especially since I had no idea what was good or not.

I think it’s great to see that many people for the event, despite the weather and the cancer walk earlier in the day. Huge lines kind of killed it for me.

My friend in passing asked me if I’d like to go to church with them because we had a long casual conversation about it. Said it was fine if I didn’t. It’s called the “Catholic” church. Never heard of it. Why is my friend forcing me to join a cult?

I’m just glad everyone posted links to the weather alerts and warnings. I always come to the r/columbus subreddit for emergency information. I just can’t depend on radio, tv, or actual news and weather websites.

It’s comforting to get onto the subreddit and read hour old emergency alerts.

There are only two driving options for tomorrow. 80 mph while tailgating or 15 mph with your emergency blinkers on. Pick your team now.

Have you heard the Credit Union of Ohio commercials?

Pam: -phone rings- "CUoO this is Pam speaking."

Mark: 'Hi Pam! What kind of loans do you offer?'

Pam: 'We offer personal, home, and auto loans. Is there anything else I can help you with?'

Mark: "No. Thank you!"

Pam: -Phone immediately rings again- "CUoO this is Pam speaking"

Mark: "Is this the same Pam I was just talking to?"

Pam: "Oh hi Mark! What can I help you with?"

Mark: "How does someone apply for an auto loan?"

Whatever higher up approved that commercial should be ashamed of themselves. Horribly written ad spot.

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We’ll never know why Mark hung up and then called right back. It’s left to the imagination.

Welcome! I was born in the Dayton area, but came to Columbus for school and just moved back after a 6 year hiatus. All kidding aside, Columbus is a great place to live, work, and have a family. If you don’t agree, I’ll meet you at the BK on 5th.

best i could get was section 302 after ten minutes. my friends who have been trying since 10 still havent gotten through

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Looks like its sold out now. Ugh these resellers and their bots have destroyed the process of seeing an even moderately big name group.

Lol at Radiohead being moderately big

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Radiohead is pretty big. I’ve had similar issues with moderately big groups too. This one pisses me off more because I’ve been a fan since The Bends/OK Computer. Should have joined the fan club (assuming they have priority tickets).

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Yeah, people don't seem to realize that this is the biggest advance in stroke care in history. I posted the sister trial here a few weeks ago also, it got like 11 comments ( I almost wish there were some way to get the mods to promote some of these studies. Help us /u/Aniridia , you're our only hope!

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I do agree this is huge. I’m an interventional radiologist and my group does the thrombotic stroke work at three hospitals, one a comprehensive stroke center. Our stroke volumes have already increased quite dramatically. In selected patients outside the old thrombectomy window, we’ve gotten some good results. If there’s a way I can promote this without abusing moderator privileges, I will.

10 points · 6 months ago · edited 6 months ago

If this occurs PSV will be down to 1 location as they already narrowed it down to 3 from the original 8.

2 of those 3 are parklands.

Greeley has also said that PSV funding the stadium 100% requires the right location. I wonder if McKalla(sp?) is a location that would allow him to do that, from what I have seen lots of things would need done to make it workable and from everything they have said so far publicly, that location hasn’t been mentioned at all by them.

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The interesting thing is a big reason for PSV wanting to leave Columbus is the desire for a downtown stadium. From what I can tell, the McKalla area is about 10 miles from downtown Austin. Mapfre stadium is about 4 miles from downtown Columbus. He's going to move the team to another city for a stadium that is even farther away from downtown?


I'm replacing carpet with bamboo in a room that abuts a hardwood hallway. The hardwood in the hallway is the typical 3/4". The bamboo is 1/2", leaving a 1/4" difference between the two floors (which will bit a little less given the underlayment under the bamboo). 1/4" doesn't seem too horrible (in my mind) if I use a use a reducer. My question is if it is worth trying to put down 1/4" or 1/8" plywood, then the bamboo to try to make the height difference less, or if 1/4" isn't something to worry about? Thanks!

3 points · 6 months ago

A transition will be cheaper but you can add 1/4" plywood underlayment to the entire bamboo area if you want the two floors even.

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Original Poster1 point · 6 months ago

Do you think a 1/4” difference would be overly noticeable or a hazard? Thanks!

1/4" won't be that noticeable. Since the flooring material is different in the two rooms, you'd need a threshold/transition even if the floor heights were the same as the bamboo won't mate up to the wood flooring and you'll want an expansion gap (which will be covered by the threshold).

The difference in height will only be apparent at the transition and it shouldn't be significant, so unless you think the 1/4" difference will bother you, just go with the transition.

Here is an cross-section of the sort of transition you'll likely need:

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Original Poster1 point · 6 months ago


Crossing fingers for Surface of the Sun

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A raid on half destroyed Mercury would be interesting.

17 points · 1 year ago

Does this peristalsis work in reverse, say if you were to vomit?

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46 points · 1 year ago

There is reverse peristalsis within the small bowel in the first phase of vomiting. After that, it's all about ab muscles and changes in abdominal and chest pressure to expel what's in the stomach.

Theres a huge personal side to medicine too like patient interaction is a big deal. Unless amazing AI are created i dont think people are gonna prefer robots over humans who actually care about them

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57 points · 1 year ago

I'm a doctor, so I'm biased, but I think this is the key. Just entering symptoms A, B and C into a computer, followed by lab values and imaging findings does not necessarily lead to a diagnosis or treatment. People with the same diseases present different ways, even if the "objective" side of their process is the same. Patient personalities can also dictate how treatment will proceed. The personal side of medicine, such as calming fears and feeling cared for, is something that I don't believe can be replicated by a computer.


I'm sure it's nothing new, but I thought it was pretty funny when it happened to me for the first time.

...and I'm nowhere near that good.

1 comment
Original Poster2 points · 1 year ago

P. Tiwari et al., Computer-Extracted Texture Features to Distinguish Cerebral Radionecrosis from Recurrent Brain Tumors on Multiparametric MRI: A Feasibility Study. AJNR Am J Neuroradiol (2016). doi:10.3174/ajnr.A4931

Background and Purpose: Despite availability of advanced imaging, distinguishing radiation necrosis from recurrent brain tumors noninvasively is a big challenge in neuro-oncology. Our aim was to determine the feasibility of radiomic (computer-extracted texture) features in differentiating radiation necrosis from recurrent brain tumors on routine MR imaging (gadolinium T1WI, T2WI, FLAIR).

Materials and Methods: A retrospective study of brain tumor MR imaging performed 9 months (or later) post-radiochemotherapy was performed from 2 institutions. Fifty-eight patient studies were analyzed, consisting of a training (n = 43) cohort from one institution and an independent test (n = 15) cohort from another, with surgical histologic findings confirmed by an experienced neuropathologist at the respective institutions. Brain lesions on MR imaging were manually annotated by an expert neuroradiologist. A set of radiomic features was extracted for every lesion on each MR imaging sequence: gadolinium T1WI, T2WI, and FLAIR. Feature selection was used to identify the top 5 most discriminating features for every MR imaging sequence on the training cohort. These features were then evaluated on the test cohort by a support vector machine classifier. The classification performance was compared against diagnostic reads by 2 expert neuroradiologists who had access to the same MR imaging sequences (gadolinium T1WI, T2WI, and FLAIR) as the classifier.

Results: On the training cohort, the area under the receiver operating characteristic curve was highest for FLAIR with 0.79; 95% CI, 0.77–0.81 for primary (n = 22); and 0.79, 95% CI, 0.75–0.83 for metastatic subgroups (n = 21). Of the 15 studies in the holdout cohort, the support vector machine classifier identified 12 of 15 studies correctly, while neuroradiologist 1 diagnosed 7 of 15 and neuroradiologist 2 diagnosed 8 of 15 studies correctly, respectively.

Conclusions: Our preliminary results suggest that radiomic features may provide complementary diagnostic information on routine MR imaging sequences that may improve the distinction of radiation necrosis from recurrence for both primary and metastatic brain tumors.

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8 points · 1 year ago

Radiologist here (IR, but trained fairly recently in neuroradiology as a resident). According to the materials/methods, only a post-contrast T1, T2 and FLAIR were available for the radiologist to determine necrosis from recurrence. There's no way any rational radiologist would think that would be a complete workup for what this study is asking. Standard DWI/SWI sequences, and newer, but nearly ubiquitous sequences such as relative cerebral blood volume (rCBV) are much more sensitive and specific for the question being asked and are widely available.

Totally understood that bit about being a radiologist and then kinda drifted from there....

I'll assume, like everything else cool that is posted as life changing, that "yes, but no and here is why" applies to your post.

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4 points · 1 year ago

I was trying to think of an analogy, but I was having a difficult time. I guess something along the lines would be asking a detective to solve a crime but not letting them use fingerprints or DNA evidence. They could do so some of the time, but why wouldn't you let them use some of the strongest tools they have if they're commonly used and widely available?

Going back to my post, you could argue the perfusion sequences (rCBV) are still not mainstream, but the diffusion/susceptibility sequences are used in virtually every brain protocol I can think of (sure, there are a few niche protocols - stealth, etc.) and I don't know why they wouldn't be included in the study. In my opinion, only allowing the radiologist to use the sequences they did meant they were forcing them to make a decision based on an incomplete and unrealistic study.

96 points · 2 years ago

I'm a gi doc and we don't use these very much because they still have a pretty high risk of infection. Most of us only use them in hospice/palliative patients.

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I'm an IR doc, and I agree. I tell my patients that it's not a matter of "if" they (tunneled peritoneal drains) will get infected, but "when." These are reserved as a palliative measure only. Denver shuts can occasionally be a longer term option, but they still fall into the palliative category.

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