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Original Poster1 point · 7 months ago

What companies/startups?

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a ton of jobs just advertised at gingko

what the fuck is the deal with "fruity".

I actually wrote to Marks and Sparks once about this.

Back in the day I was interested but uninformed. I read the back of about seven bottles at the Marylebone train station Marks and Spencers, every single wine's main descriptor was 'fruity'. How was I supposed to know the difference between the bottles from regions I was unfamiliar with and with grape varietals that weren't listed because Europe.

Okay so wine is fruity. And yes some people are total wank jobs about how they describe their wine 'sour notes of a 19th century nun's salty butt hole dribbled in acacia honey' and the like. I mean fine, if that's what it tastes like to you that's great. But really, descriptors are supposed to convey the taste from one person to another.

Fruity is such a generic term. What fruit? apples? like some of those weird orange wines with tons of carbonic maceration? Cherries like some of the really bitter reds? grapefruit like some of the odd and semi-hidden obscure Loire red varietals (I'm looking at you pineau d'aunis and groslot). Or is fruity supposed to mean just 'generic grape flavours' in which case surely it should be omitted as it would be sort of just a default setting?

Anyway. That's my fruity rant. I'm sorry if it hits a nerve or comes out as rude. Also I'm sorry for bringing up a nun's arsehole.

Smoke taint is an issue in Australia where fires are a regular occurence, particularly in the large production areas in south australia which can get very hot and dry near harvest (january/febuary). January is often the bushfire season and the waxes and cutins do trap a lot of smoke. Smoke taint gets worse in a wine over time and there are significant funds going in to develop methods ameliorate this. However the market is also in glut so it's not neccessarily a huge priority - it won't affect majority of the grapes in one year, though it may devastate a few wineries in one year.

I would hazard a yes that there would be impacts of pollution taint in wine.

Hahaha, oh please. Keneally was 10x worse. Lipstick on a pig of the most corrupt government since the Rum corp.

You can thank him for keeping the NSW economy spinning by actually funding and building infrastructure projects instead of NSW Labor sitting on their hands for a decade.

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the two who slunk away into the night without ever accepting any real public scrutiny are Bob Carr and Eric Rozendaal. I recall reading about the ICAC hearings and Rozendaal was sitting there stony faced making sure no-one brought him down with them. He is one scary sinister motherfucker. I would not be surprised if he's into some seriously crooked stuff.

Interestingly for those who appear to be under the false pretense that Keneally is somehow clear of the chinese influence, it's important to take note that now both Bob Carr and Eric Rozendaal work directly for chinese interests! how about that!

Shorten has solidified that I'll be paying my fine instead of voting in the next election. Fuck you mate I'll be out on the yacht instead, not wasting my time making a decision between dumb and dumber.

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too bloody right

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looks like a normal australian primary school playground in summer to me!

I don't know what level of your career you're at but a postdoc in australia gets 90k and a better standard of living than in USA, the salary in continental europe (but not the UK) is not high but the lifestyle, healthcare (even for foreigners) etc etc is way better than USA.

And as a native english speaker you're likely to be sought after in foreign language countries where they always love an extra brain to filter their papers through for grammatical checks.

I know there's that whole myth that USA is the best, but really, is it worth it? In my opinion fuck no.

I know it may sound grandiose, but geez, do yourself a favour, move to spain or france or germany, you may or may not have to learn a second language but it's so not as bad as you'd think.

I've done this, a japanese friend of mine has done this, russian friends, american friends, not one single one has regretted the decision. Once you're on your way somewhere else, if you really really want to get back into the situation where you get paid 9 months of a year and consider yourself to have 'made it' because you're tenured, then you can always apply for those jobs from another country.

I've honestly been thinking of doing this just to expand my horizons, see other countries. Australia would be awesome, or somewhere in Europe... I'm also considering doing a PhD overseas since it'll only be 3 years on top of my masters vs. going back here in the US where it'll be 5-7 years. How are salaries in these places for a MSc with good experience?

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I went to france for mine, i was living on a wage equivalent to a postdoc there, which isn't a bankers salary but is enough to live a very comfortable life if you're not in paris (france = not in paris for anything to do with affordability/lifestyle).

The medical care was great, and while I didn't I know others that also applied for CAF as non-french nationals they were eligible because they were students in the french student. CAF is essentially a social welfare for people living in france. I have no idea how my non-EU citizen friend got it but she was eligible for it and scored a few thousand euroes. Mind blowing but true.

You won't make a ton of money but in the context of french salaries you'll do alright and have enough to live comfortably while you're doing your PhD.

Shorten can't spare his vote when he's trying to chip away at the LNP's majority.

You can always rely on Shorten to do whatever will score political points in the short term, regardless of ethical or integrity issues and no matter how hypocritical it makes him look. It's the same reason why Shorten made Labor vote against their own policy on budget savings measures when the LNP tried to pass them.

Goes to show it's impossible to be too corrupt to stay in the Labor party. If you doubt that, ask Eddie Obeid.

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what bothers me, is how closely Eddie Obeid, Kristina Keneally and Sam Dastyari all are connected, yet all three have very cleanly copied from Bob Carr's revisionist history modus operandi.

Kristina Keneally has been in the media a lot recently, and everyone is talking about how 'her testimony put Obeid in prison', yet the reality is plain as day that ICAC criticised her, not lauded her, it wasn't her testimony that put him in prison at all. ICAC actually criticised her for enabling Ian Macdonald and Eddie Obeid.

Sam Dastyari was a protege of obeid clean and simple. He was in obeid's office every single day, but when obeid went 'out of fashion' they dropped him like a stone.

Shorten is absolutely in line with these two shady characters. It's not that he's beholden to them because of the right of the ALP, shorten is the right of the ALP.

He needs to be replaced; shorten, and dastyari.

is it some sort of scandal relating to copper? did someone order gold and got copper instead? Why coppergate??

Can I edit carrot genes to make them produce caffeine? End result would be caffeinated carrots.

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doesn't require CRISPR

Easiest way to make this happen?

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agrobacterium? a bunch of genes? a biosensor for caffeine which confers fitness to carrots with elevated caffeine levels? many options

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Usually that's right before I accidently suck up my pellet. I'm so damn clumsy.

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stack a p1000 tip into a p200 tip, and you've got yourself a tip which will suck up large volumes but with a small hole - super useful for really getting the very last bit of ethanol off your DNA preps

work for the beverages industry. great perks, fun people, great job.

my guess would be maintenance and dissemination of a large library of DNA fragments and e coli strains and what have you, as well as the administrative overhead of organising an international level genetics project across a bunch of different countries all with different gene technology regulations, and health and safety issues, and biosafety and ethics etc etc, in a legal and safe and fun engaging way. As well as all the communication, and even organising and everything like that. I guess if something along the lines of $5000 for all that per team sounds like a rip off, you can start your own iGEM competition? I don't know where you live, byt where I am, getting the rights to import/export genetically modified organisms is already pretty bloody expensive.

[deleted]
11 points · 10 months ago

Good on you Gladys!

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she is way better than Baird, and in a completely different league than Carr/Keneally (like there's a difference). So nice to have a good premier.

what the fuck does swearing have to do with Christianity?

well i don't know but this job seems to pay pretty well and these two postdoc jobs pay over 90,000 a year which is over 70k a year USD, and this postdoc is advertised at 99k a year which is almost 80k US a year, and in the country they're advertised in, that's more than enough to get by and live pretty large....

I have limited sympathy for people who choose to support the broken US research/education system...

any archaeologists here?

would these have been special for a priestess or something? or is it the kind of thing that your average 2nd century rich greek lady would have worn when she was putting the bins out, or taking the dog for a walk, or hosting a greek orgy

Fucking seriously?

This mob couldn't organise a piss-up in a brewery or a root in a brothel. So desperate to wave the flag "Look at moi! Look at Moi! I'm making trains" that they can't even match the gauge and tram dimensions?

What a joke.

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i suppose at least, unlike the ALP under kenneally, they didn't acquire a bunch of land promising a metro, then cancel the metro and sell the land on the cheap to their mates.

it's a shit fight for sure, but it could be worse.

No, they didn't.

Instead, they bankrupted local businesses with unecessary and aggressive legislation, and they forcibly removed citizens from their homes. Then they allowed their party donors to get the land for pennies on the dollar, to build cheap apartments with no thought to local infrastructure, and to build roads at 10x and 20x the quoted expense. And then some of them used their dying family members as an excuse to quit politics, only to take a job with one of the major financial brokers of the entire ordeal a month later.

This 'whataboutism' has to stop. Both sides are fucked. This is not 'left vs right' point scoring. This is 'us vs them'. And it will continue to get worse until we have a legitimate third option.

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you're totally right! I agree 100% but almost every comment I read in Australian subreddits is DAE vote ALP? including the comment I replied to.

I did stipulate it is a shit fight in my closing sentence; I agree this is total Disney infrastructure, and also; apparently a former rugby team owner/generic rich dude with no experience was put in charge of the whole project from the start.

But I still feel like people who comment on reddit are all sort of "ALP" would have done it better - despite ample evidence to the contrary.

Sadly no. The technology to specifically turn genes on and off is in its infancy (basically you use a version of crispr fused to gene-activating proteins).

Also, the 'big boob genes' you have may not be off. In fact, you could have 'small boob genes' that are way too on! We don't really know how those genes work. It might be more complicated than just gene expression levels. We just know women with those gene variants tend to have larger boobs.

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That sounds a little wrong - surely the genes for bigger boob size are controlled by hormones... just rub a bit of boob hormone on them and shwooompf they'll grow overnight.

well not really, but in all seriousness I think your answer sounds a little bit overcomplicated.

OKAY, here's the situation.

we saw the exponential decrease in the cost of DNA sequencing we are also seeing a rapid decrease in the cost of DNA synthesis.

Today I had a chat to a senior academic who has gone away to a conference and wanted to fill me in on a plant protein engineering project someone else was working on and how it's unlikely to work for me because they had to try 100s of combinations to get it to work.

To contextualise why the cheapness of DNA synthesis will help overcome major barriers in terms of time and experiment design that CRISPR's success as a medical treatment fails, I think my thought about what this prof said vs my thoughts would have been 5 years ago when I wasn't in a synthetic biology lab will demonstrate.

me 5 years ago had the prof said that to me?

This is impractical, I won't be able to effectively try 100s of combinations without any assurance that this will work, it will take years to meticulously design and test in a stepwise fashion

synthetic biology me:

I can do this because I can just buy 200 random and different combinations and see which ones work in one experiment

Essentially, the fact that now it's no big deal for me to order 200 140bp constructs that code a whole library of different protein domains and test them all in about a week is a major game changer in the way I can conceptualise doing an experiment.

In relation to how that will effect CRISPR? I think the way we are starting to do science now will possibly speed up the ability for a wide range of scientists to do DNA experiments where previously cloning etc was cost and skill prohibitive. And I think that will expedite results for medical outcomes for things like CRISPR.

get out before 6 months or stay for four years at least.

if youre a molecular biologist in a molecular biology lab it can't be that bad.

if you're already producing data for a paper 3 months in, and you'll be on that article it's not that bad.

but if you have no interest or enthusiasm for the project, the lab and the group, get out.

if this is interesting to anyone I would highly suggest you follow @GaetanBurgio he's the sassiest coolest CRISPR/gene editing researcher out there, often calling out bullshit despite the potential to threaten his job, and posts great things from retraction watch

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