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J42S commented on a post in r/nutrition
J42S 2 points

Due to massive amount of misinformation and bad science its a hard question to answer if you dont want to spend alot of time researching.

I would suggest that you do an experiment on your self. try X way of eating for say 30 days and so how you look, feel and perform.

Its great if you can get some objective measures in addition to the subjective. I would suggest getting https://ouraring.com/ . i have tried many different devices and this ones wins by a long shot. measures, sleep, RHR, HRV, Temp, activity, recovery.

I would suggest getting a cheap glucose monitor.

There was a really interesting recent study that showed that different people can have widely different glucose response from identical meals. In fact some have higher blood glocose response than what should be possible from the amount eaten which suggest a immune reaction and glucose being released from the liver. how2

If you want a suggestion for what WOE you should try first i would suggest an elimination diet which excludeds the foods that are most likley to be problematic and immunostimmulatory for a period of time than reintroducing them one at the time and see what works and what doesnt. Dr Rangan Chatterje in the great BBC TV-series Doctor in the house use this approach with many of his patients with great results.

J42S commented on a post in r/Supplements
J42S 1 point

I heard that some people have adverse reaction to the mk-7 version of k2 so could try to switch to mk-4. think the side effect typicaly are anxiety and or irregular heartbeats or something like that.

here is a good resource on possible side effects of vitamn-d https://www.vitamindwiki.com/Side+Effects+and+Warning+for+vitamin+D

It appears that about 1 person in 300 people have an allergic type reaction vitamin D within days. (Have no specific reference - it is just an impression from reading 7,000+ articles on vitamin D) The allergic reaction may include itchy skin, hives, intestinal upset

https://www.vitamindwiki.com/Overview+Rare+Allergic+reaction+to+vitamin+D

J42S commented on a post in r/zerocarb
CrumbledFingers 2 points

I'm not sure if Crohn's works the same way. My IBS was very diet- and mood- dependent, and I know there are more underlying factors with Crohn's. I hope you get some relief!

J42S 1 point

Have you looked into crohns and vitamin-d?

Crohn’s helped by 5000 IU vitamin D

A number of anecdotes of people with chrones getting better with high doses of vitamin-d

J42S 1 point

Marty Kendall is an civil engineer from Brisbane, Australia and the husband of a Type-1 Diabetic. He has a strong interest in improving the health of his family and others by analysing what determines optimal nutrition and he shares his findings via the blog https://optimisingnutrition.com

In this video, Marty discusses how he has used data from the food insulin index and applied multi criteria analysis to determine the optimal diets to suit particular nutritional goals. He has used this data to create the 'Nutrient Optimiser' algorithm which formulates a personalised health fingerprint for optimising nutrition.

For more details on the 'Nutrient Optimiser' visit; https://nutrientoptimiser.com/

Optimising Nutrition Facebook group; https://www.facebook.com/groups/optimisingnutrition/

J42S commented on a post in r/nutrition
J42S 1 point

seed oils are high in omega 6 which is inflammatory. chronic inflammation seems to be linked with every chronic disease. so it seems wise to avoid. its also highly evolutionary novel to consume high amounts of omega 6. we have only done it for less than 100 years.

https://www.alexfergus.com/blog/pufa-s-the-worst-thing-for-your-health-that-you-eat-everyday

J42S commented on a post in r/Supplements
dizson 43 points

Don't try this at home kids, just because someone wrote this and run an experiment, you don't want yourself to be in danger. Scientific studies showed that 4k IU was enough to get people into normal D vitamin level range.
It's a megadose of a micronutrient, and we don't know all its effects on the body. Megadoses shouldn't be used outside of controlled clinical settings. This could be dangerous...

Anecdotally, people respond differently to supplements.

J42S 2 points

General advice on dosage is almost always wrong.

there is not a good general dose since there is massive variability when it comes to dose response so bloodwork is the best way of figuring out your optimal dose: link

J42S commented on a post in r/science
anonymouse5440 3 points

Probably not relevant to humans as we evolved eating WAY more fat than mice did.

This may not be true.

Meat consumption certainly played a role in human development -- there's no denying that -- but there's evidence that humans may have evolved eating a mostly vegetarian diet. Compared to mice -- some species of mice anyhow -- who regularly eat various species of insects, worms, and the remains of larger species, it's legitimately possible that mice evolved eating significantly more fat (as a percentage of their size) than humans.

J42S 6 points

http://www.scienceschool.usyd.edu.au/history/2009/media/lectures/4-brand-miller-chapter.pdf

See page 34-35

looking at the plant to animal proportion of 229 hunter gatherer societies the mean animal consumption was 68%. And there were 0% vegetarian societies, all were omnivore.

J42S 2 points

Abstract

Because serum magnesium does not reflect intracellular magnesium, the latter making up more than 99% of total body magnesium, most cases of magnesium deficiency are undiagnosed. Furthermore, because of chronic diseases, medications, decreases in food crop magnesium contents, and the availability of refined and processed foods, the vast majority of people in modern societies are at risk for magnesium deficiency. Certain individuals will need to supplement with magnesium in order to prevent suboptimal magnesium deficiency, especially if trying to obtain an optimal magnesium status to prevent chronic disease. Subclinical magnesium deficiency increases the risk of numerous types of cardiovascular disease, costs nations around the world an incalculable amount of healthcare costs and suffering, and should be considered a public health crisis. That an easy, cost-effective strategy exists to prevent and treat subclinical magnesium deficiency should provide an urgent call to action.

Moneybags99 4 points

Is there anything vitamin D doesn't help with?

J42S 2 points
EvoEpitaph 2 points

Curious, does 4000 iu per day for a month not cause vitamin d toxicity?

J42S 1 point

in a month no.

eventually? very unlikely but get your blood tested to be safe.

https://grassrootshealth.net/document/vitamin-d-toxicity/

No toxicity was observed at levels below a 25(OH)D serum level of 200 ng/ml (500 nmol/L), and no toxicity was observed in studies reporting a daily vitamin D intake below 30,000 IU.

Also there was a recent study that concluded that RDI for vitamin-d is many times to low due to a statistical error, here is a reddit thread on the study:

The Big Vitamin D Mistake. A statistical error in the estimation of the recommended dietary allowance (RDA) for vitamin D was recently discovered; in a correct analysis of the data used by the Institute of Medicine, it was found that 8895 IU/d was needed for 97.5% of individuals.

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