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kndofblue commented on a post in r/biology
kndofblue 2 points

If by embryo loss you mean death after fertilization, look into maternal effect lethal genes and early axis formation! MEL genes are super interesting and control a lot of early development and embryogenesis. Some other keywords you could use for your search are blastula, gastrulation and C. elegans (really key model organism used a lot in dev bio). A second genetic factor that might be more accessible is errors in recombination. Keywords like chromosome nondisjunction, meiosis, aneuploidy can help you get started

Nobrr 1 point

Thanks for the start! On embryo loss definition, Im taking this to mean something along the lines of miscarriage.

I've seen the term aneuploidy used, however I thought this was a blanket term used to describe cells with an incorrect number of chromosomes? Not necessarily a cause.

kndofblue 2 points

Incorrect number of chromosomes is typically lethal to the developing embryo. For example, Turner's syndrome is the only monosomy that won't kill the embryo.every other monosomy is lethal, you almost always need 2 (and only 2) copies of each chromosome. Many of the exceptions to the lethality of aneuploidy are sex-chromosome related, but the vast majority of errors resulting in incorrect number of chromosomes actually will cause embryo death.

kndofblue commented on a post in r/evolution
kndofblue 7 points

Overwhelming evidence in favour of a theory doesn't make it a fact, but it is the accepted paradigm for understanding life on earth. If you're looking for some evidence in support of evolution to convince you, you should check out Lenski's E. coli lab - it's a great model system that shows how evolution can operate at different timescales. Over 50,000 generations of E. coli have been raised to show the progression of random mutation and natural selection.

mrbananas 2 points

The best biological definition of evolution is the change of allele frequency within a population. This phenomenon is observable fact that has been documents, recorded and measured. You can measure allele frequency, you can measure its change over the course of generations.

Changes of traits within a population is a measurable fact. Its as simple as count the number of finches with long beak and short beaks on an island, then count that number again next year, then do it again for 8 more years.

kndofblue 1 point

I appreciate that for sure, I just meant more that scientific "fact" is a problematic concept - as in, nothing is a fact, all empirical data and theory are subject to reanalysis - but this post isn't necessarily about the philosophy of science or the semantics of the issue. Observable and measurable phenomena support the theory of evolution to the point that it's irrational to reject it (just a more careful way of phrasing things)

kndofblue commented on a post in r/linguistics
kndofblue 9 points

It's probably the most common, but not the only example of old English given in the context of historical linguistics. as an introduction to the concept of language evolution it's a good place to start. The fact that it is formal prose is useful for comparative study - compared to Chaucer, for example, or the King James Bible which are also both formal texts. The variability of language makes it hard to establish good lines for comparison analysis in more colloquial dialects, especially since English lacked a standardized orthography at the time. So it's a good example if you're studying English historically both because it is a pretty stark contrast to later forms of English (which is exciting/interesting if you're just starting out in the field), and because it's the closest thing to a standardized example of language from that time.

kndofblue commented on a post in r/mcgill
kndofblue 3 points

upstairs in the islamic studies library if you're quiet (some good solo desks at the end of rows of bookshelves), or the rooms in leacock adjacent to snax. the individual booths have opaque glass doors, just check the posted sheets to see they're not booked for TA office hours first

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